I work with statistical and population genetics. Recently, in particular methodologies related to
I am a member of the Academy of Finland Centre of Excellence in Complex Disease Genetics 2018-2025.
Mathematically and statistically oriented students with interest in modern computational methods for high-dimensional problems, and/or students with interest in applications of computational methods in human genetics, be in touch by email.
Previously completed PhD theses that I have supervised are listed below.
|Kerminen, Sini||2021||Fine-scale genetic structure and polygenic scores in Finland||M. Pirinen (UH) & S. Ripatti (UH)|
|Benner, Christian||2019||FINEMAP: a statistical method for identifying causal genetic variants||M. Pirinen (UH) & S. Ripatti (UH)|
|Cichonska, Anna||2018||Machine learning for systems pharmacology||J.Rousu (Aalto), T.Aittokallio (UH), M.Pirinen (UH)|
Msc students interested in Msc theses in statistics in general, or statistical genetics / statistical population genetics in particular, be in touch by email.
Completed Msc theses that I have supervised at University of Helsinki or I have been advising on at Aalto University are listed below.
|Malmberg, Anni||2020, UH||Visualizing the genetic population structure in Finland with principal component analysis and generative topographic mapping|
|Ottensmann, Linda||2020, UH||Comparing the performance of the gene prioritization methods DEPICT and MAGMA on genome-wide association studies of schizophrenia using the Benchmarker framework|
|Mihaylova, Mihaela||2019, Aalto||A Study of LDL aggregation and its correlation with the LDL lipidome and clinical data in bariatric surgery patients|
|Karell, Pauliina||2018, UH||Robustin lineaarisen sekamallin soveltaminen DNA-metylaatiointensiteetin mallintamiseen|
|Hautakangas, Heidi||2018, UH||LD Score regression for estimating and partitioning heritability of lipid levels in the Finnish population|
|Tuominen, Samuli||2018, UH||Association between polygenic methylation scores and maternal phenotypes|
|Ruotsalainen, Sanni||2017, UH||Univariate and multivariate statistical tests in genetic association studies|
|Lääperi, Mitja||2015, UH||Linear mixed models for estimating heritability and testing genetic association in family data|
|Sandoval Zarate, America||2015, UH||Discovering disease trajectories from the Finnish Hospital Discharge Register with the MCL algorithm|
|Kerminen, Sini||2015, UH||Genetic population structure in Finland: an advantage of haplotype information over independent genetic markers|