Problems with Chandra RK (1992) Lancet 340:1124-7
Effect of vitamin and
trace-element supplementation
on immune responses and infection in
elderly subjects.
http://dx.doi.org/10.1016/0140-6736(92)93151-C
PubMed abstract
Collected
by:
Version
May 29,
2012
The Chandra 1992 paper in Lancet has
been particularly
influential in the field of nutrition and infections diseases.
It has been cited over 340 times by
July 2009 (Web of Science).
Chandra had been a respected nutritionist, e.g.
Chandra received the McCollum award in 1990
http://www.nutrition.org/about-asn/awards/past-recipients
E.V. McCollum Award:
Given to a clinical investigator who is perceived currently as a major
creative force, actively generating new concepts in nutrition and
personally seeing to the execution of studies testing the validity of
these concepts. The cash award and inscribed plaque are sponsored by
Wyeth Nutrition.
Ranjit Chandra has twice been nominated for the Nobel Prize in
medicine.
He is an officer of the Order of Canada, the holder of five honorary
doctorates and a visiting professor at universities on four continents.
http://www.thecanadianencyclopedia.com/index.cfm?PgNm=TCE&Params=M1ARTM0010546
A summary of the story:
http://en.wikipedia.org/wiki/Ranjit_Chandra
See discussions of
the story:
Kondro W, Hebert PC (2007) Research misconduct? What misconduct?
CMAJ
http://www.cmaj.ca/cgi/content/full/176/7/905
Margetts, Barrie (2006) Stopping the rot in nutrition science.
Public Health Nutrition
http://dx.doi.org/10.1079/PHN2006947
Roberts, Seth (2006) Dealing with scientific fraud: a proposal.
Public Health Nutrition
http://dx.doi.org/10.1079/PHN2006963
Sterken, Elisabeth (2006) The impact of scientific misconduct on child
health
Public Health Nutrition
http://dx.doi.org/10.1079/PHN2006951
Sternberg, Saul & Roberts, Seth (2006) Nutritional supplements and
infection in the elderly: why do the findings conflict?
Nutr J
http://www.nutritionj.com/content/5/1/30
Marcovitch,
Harvey (2006) Research misconduct: can Australia learn from the UK's
stuttering system?
MJA
https://www.mja.com.au/public/issues/185_11_041206/mar11049_fm.html
Kouzin J, Unger K (2006) SCIENTIFIC MISCONDUCT: Cleaning Up the Paper
Trail
Science
http://www.sciencemag.org/cgi/content/summary/312/5770/38
BMJ:
White
(2004) Three journals raise doubts on validity of Canadian studies
[news].
http://dx.doi.org/10.1136/bmj.328.7431.67
correction: http://www.bmj.com/cgi/content/full/328/7434/257
e-letters: http://bmj.bmjjournals.com/cgi/eletters/328/7431/67
and… more in BMJ:
The secret life of Dr Chandra
http://www.bmj.com/cgi/content/full/332/7537/369
Suspected research fraud: difficulties of getting at the truth
http://www.bmj.com/cgi/content/extract/331/7511/281
Investigating allegations of scientific misconduct
http://www.bmj.com/cgi/content/extract/331/7511/245
Investigating the previous studies of a fraudulent author
http://www.bmj.com/cgi/content/extract/331/7511/288
Validity of Canadian studies: Response of editor of BMJ
http://www.bmj.com/cgi/content/full/328/7437/465-b
***
Smith (2005) Research misconduct: the poisoning of the well
JRSM
http://www.jrsm.org/cgi/content/full/99/5/232
Shenkin SD (2002) Supplementation and the elderly: dramatic results?
Nutrition
http://dx.doi.org/10.1016/S0899-9007(02)00768-2
Roberts S (2003) Do nutritional supplements improve cognitive function
in the elderly?
Nutrition
http://dx.doi.org/10.1016/S0899-9007(03)00025-X
...and...
http://www.psych.upenn.edu/~saul/critiquetext.pdf
http://www.blog.sethroberts.net/2006/11/
(Nov 23, 2006)
http://sethroberts.net/chandra/index.html
http://sethroberts.net/chandra/2006-02-27_Dealing_with_scientific_fraud-A_proposal.pdf
Carpenter K, Roberts S, Sternberg S (2003) Nutrition and immune
function: a 1992 report
Lancet
http://dx.doi.org/10.1016/S0140-6736(03)13755-5
Meguid M (2005) Retraction [of Chandra's paper]
Nutrition
http://dx.doi.org/10.1016/j.nut.2004.12.002
http://www.ncbi.nlm.nih.gov/pubmed/15793927
see also: http://dx.doi.org/10.1016/S0899-9007(03)00023-6
*****
Payne (2005) Nutrition retracts 2001 paper: study by Chandra had been
questioned since 2003.
The
Scientist
http://www.the-scientist.com/news/20050303/02/printerfriendly
http://www.the-scientist.com/article/display/22614/
http://www.the-scientist.com/news/display/50214/
http://www.thescientist.com/news/display/52921/
http://www.sciencemag.org/cgi/content/summary/303/5657/465b
http://www.cbc.ca/canada/newfoundland-labrador/story/2007/01/23/chandra-review.html?ref=rss
http://www.cbc.ca/canada/newfoundland-labrador/story/2005/03/02/nf-chandra-retraction-20050302.html
http://www.cbc.ca/health/story/2004/06/10/chandra040610.html
http://www.medbroadcast.com/channel_health_news_details.asp?news_id=7452&rss=67&rid=999999&channel_id=1039&rot=3
http://www.canada.com/nationalpost/news/bodyandhealth/story.html?id=47843098-745d-479d-91b4-6615b7f98585
The MUSE:
Memorial's Student Newspaper
http://www.themuse.ca/view.php?aid=39948
http://www.themuse.ca/view.php?aid=39320
http://www.themuse.ca/view.php?aid=38810
http://www.themuse.ca/view.php?aid=38531
http://www.themuse.ca/view.php?aid=38530
http://www.themuse.ca/view.php?aid=38529
http://www.themuse.ca/view.php?aid=38510
http://www.themuse.ca/view.php?aid=38488
http://www.med.mun.ca/munmed/181/pg6_181.htm
https://www.infactcanada.ca/Chandra_Feb72006.htm
https://www.infactcanada.ca/Winter_2006_Pg_1_2.htm
https://www.infactcanada.ca/Chandra_Jan30_2006.htm
http://www.rediff.com/us/2000/may/04us3.htm
http://www.thefactsaboutfitness.com/news/research.htm
