After Rose & Bown, 1982, McKenna & Bell, 1997, Thewissen, Williams & Hussain, 2001 and Alroy, 2002

<==o †Plesiadapidae Troussart, 1897 [incl. Saxonellidae]
   |?- †Jattadectes mamikheli Thewissen, Williams & Hussain, 2001
   |?- †Pandemonium Van Valen, 1994
   |--o †Saxonella D.E. Russell, 1964 [Saxonellidae D.E. Russell, 1964; Saxonellinae D.E. Russell, 1964 sensu McKenna & Bell, 1997]
   |  |-- †S. crepaturae
   |  `-- †S. naylori
   `--o †Plesiadapinae Troussart, 1897
      |-- †Pronothodectes gaoi Fox, 1990b [genus Pronothodectes Gidley, 1923]
      `--+-- †Pronothodectes matthewi
         `--+-- †Pronothodectes jepi
            |--o †Nannodectes Gingerich, 1975
            |  |?- †N. gidleyi
            |  |-- †N. intermedius
            |  `--+-- †N. gazini
            |     `-- †N. simpsoni
            `--+-- †Plesiadapis praecursor
               `--+-- †Plesiadapis anceps
                  |--o †Chiromyoides Stehlin, 1916
                  |  |-- †C. campanicus
                  |  |-- †C. caesor
                  |  |-- †C. minor
                  |  |-- †C. potior
                  |  `-- †C. major
                  `--+?-o †Platychoerops Charlesworth, 1855 [Miolophus Owen, 1865; Subunicuspidens Lemoine, 1887]
                     |  |-- †P. daubrei
                     |  `-- †P. richardsoni
                     `--o †Plesiadapis Gervais, 1877 sensu stricto? [Tricuspidens Lemoine, 1887;  Nothodectes Matthew, 1915; Menatotherium Piton, 1940; Ancepsoides D.E. Russell, 1964]
                        |?- †P. walbeckensis
                        |?- †P. remensis
                        |?- †P. tricuspidens Gervais, 1877
                        |?- †P. russelli
                        |-- †P. rex (Gidley, 1923)
                        `--+-- †P. gingerichi
                           `--+-- †P. churchilli
                              |--+-- †P. fodinatus
                              |  `-- †P. dubius (Matthew, 1915)
                              `--+-- †P. simonsi
                                 `--+-- †P. gingerichi
                                    `-- †P. cookei

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