After McKenna & Bell, 1997

<==o †Megatheriidae Gray, 1821 (jättiläislaiskiaiset) [Synonyms]
   |--o †Schismotheriinae Mercerat, 1891 [Schismotheriidae Mercerat, 1891; Schismotheriinae McKenna & Bell, 1997; incl. Metopotherini Ameghino, 1894]
   |  |-- †Diheterocnus Kraglievich, 1928 [Heterocnus Kraglievich, 1925]
   |  |-- †Schismotherium Ameghino, 1887 [Metopotherium Ameghino, 1891]
   |  |-- †Synhapalops Kraglievich, 1930
   |  |-- †Hapaloides Ameghino, 1902
   |  |--o †Hapalops Ameghino, 1887 [Synonyms]
   |  |  `-- †H. elongatus
   |  |-- †Pelecyodon Ameghino, 1891 [Uranokurtus Ameghino, 1894; Adiastemus Ameghino, 1894]
   |  |-- †Parapelecyodon Scillato-Yané, 1981
   |  |-- †Analcimorphus Ameghino, 1891
   |  |-- †Hyperleptus Ameghino, 1891
   |  `-- †Neohapalops Kraglievich, 1923
   `--o †Megatheriinae Gray, 1821 (jättiläislaiskiaiset) [Synonyms]
      |-- †Nothrotheriini Ameghino, 1920 [Synonyms] [are megalonychids (de Muizon, McDonald, Salas & Urbina, 2003) or separate family (de Muizon, McDonald, Salas & Urbina, 2004)]
      `--o †Megatheriini Gray, 1821 [Megatheriadae Gray, 1821; Megatheriini Winge, 1923; Megatheriini McKenna & Bell, 1997]
         |--o †Propotheriina Ameghino, 1894 [Prepotheridae Ameghino, 1894; Planopsidae Scott, 1904; Planopsinae Winge, 1923]
         |  |-- †Proprepotherium Ameghino, 1904 [Proprepotherium Ameghino, 1904]
         |  |-- †Planops longirostratus Ameghino, 1887 [Paraplanops Ameghino, 1891; Prepotheriops Ameghino, 1904]
         |  `-- †Prepotherium Ameghino, 1891
         `--o †Megatheriina Gray, 1821 [Megatheriidae Gray, 1821]
            |--o †Megathericulus Ameghino, 1904
            |  `-- †M. patagonicus
            |?- †“Plesiomegatherium” triangulatum (nomen vanum sensu De Iuliis, Ré& Vizcaíno, 2004)
            |-- †“Plesiomegatherium” halmyronorum Cabrera, 1928
            `--+-- †Promegatherium Ameghino, 1883 [Eomegatherium Kraglievich, 1926]
               |--o †Megatheridium Cabrera, 1928 [Pliomegatherium Kraglievich, 1930]
               |  `-- †M. annectens
               |--o †Pyramiodontherium Rovereto, 1914 [taxonomic history]
               |  |-- †P. bergi (Moreno & Mercerat, 1891) [taxonomic history]
               |  `-- †P. scillatoyanei de Iuliis, Ré & Vizcaíno, 2004
               |--o †Megatherium Cuvier, G., 1796 [Synonyms] Plioc. SA., Pleistoc. SA. NA.
               |  |-- †M. altiplanicum Saint-André & de Iuliis, 2001
               |  `--+-- †M. tarijense Gervais & Ameghino, 1880
               |     |-- †M. medinae Philippi, 1893
               |     |-- †M. istilarti Kraglievich, 1925
               |     |-- †M. parodii Hoffstetter, 1949
               |     |-- †M. sundti Philippi, 1893
               |     |-- †M. lundi-sejoi?
               |     |-- †M. gallardoi Ameghino & Kraglievich, 1921
               |     `-- †M. americanum Cuvier, G., 1796
               |--o †Eremotherium Spillmann, 1948 [Schaubia Hoffstetter, 1949; Schaubitherium Hoffstetter, 1950; Pseuderemotherium Paula Couto, 1954]
               |  |-- †E. sefvei de Iuliis & Saint-André, 2001
               |  |-- †E. eomigrans
               |  `-- †E. laurillardi (Lund, 1842) [E. mirabile (Leidy, 1855); E. rusconii (Schaub, 1935)]
               |--o †Ocnopus Reinhardt, 1875 [Parascelidodon Hoffstetter, 1952; Megatherium Cuvier, G., 1796]
               |  `?- O. laurillardi Lund, 1842 [Megatherium laurillardi Lund, 1842; = Eremotherium laurillardi (Lund, 1842)]
               `-- †Perezfontanatherium Roselli, 1976

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