Vitamin C for preventing and treating pneumonia
Cochrane review
doi:10.1002/14651858.CD005532.pub3
https://helda.helsinki.fi/handle/10138/225862
https://www.mv.helsinki.fi/home/hemila/CP/2013_Coch_Pneu_CD005532.pdf
by Harri Hemilä and Pekka Louhiala
Summary of the findings and a discussion of implications:
J R Soc Med 2007
JRSM 2007 in PMC
The
2013
version is available here:
https://www.mv.helsinki.fi/home/hemila/CP/CochranePneumonia_2013.pdf
In
2016
we
updated
the review, and the updated review is available here:
https://www.mv.helsinki.fi/home/hemila/CP/CochranePneumonia_2016.pdf
Cochrane Collaboration rejected the above 2016 update for reasons that are not related to the scientific validity of the review.
In June 2016 we responded to reviewer comments:
https://www.mv.helsinki.fi/home/hemila/CP/ARI_June2016_pneu_responses.pdf
Our responses to the comments of
Mark Jones from the Cochrane Acute Respiratory Infections (ARI) group,
are available here:
https://www.mv.helsinki.fi/home/hemila/CP/MarkJones_pneu_responses.pdf
None of the Mark Jones' comments pointed out any genuine scientific problems in our 2016 update.
Many of his comments reveal that he did not read our 2016 update carefully, see youself.
The rejection decision in February 2017 by Chris Del Mar did not point out any specific scientific reasons for the rejection:
https://www.mv.helsinki.fi/home/hemila/CP/ChrisDelMar_2017_pneu_comments.pdf
None of the above comments pointed out any genuine scientific problems in our 2016 update, read the comments and responses yourself.
References available via internet:
Contents
Included trials
Excluded trials
Other references
Harri Hemilä
Department of Public Health,
University of Helsinki, Helsinki, Finland
harri.hemila@helsinki.fi
Home
:
https://www.mv.helsinki.fi/home/hemila
Papers on pneumonia and other serious infections:
https://www.mv.helsinki.fi/home/hemila/vitc_pneumonia.htm
Oct 25, 2022
Included trials
Glazebrook 1942_PMC
Glazebrook 1942 ch
Glazebrook 1942 tables
Comment in BMJ 1942 June by the authors
Comment in BMJ 1942 commentary
Comment in BMJ 1942 Nov by the authors
Comment in BMJ 1944 Nov by the authors
Description of the study backgound via
an earlier paper in J Hyg (1941)
Pauling's analysis
https://scarc.library.oregonstate.edu/coll/pauling/rnb/31/31-103.html
https://scarc.library.oregonstate.edu/coll/pauling/rnb/33/33-034.html
https://scarc.library.oregonstate.edu/coll/pauling/rnb/33/33-035.html
Hunt 1994 ch_ZENODO
Hunt 1994 ch
Hunt 1994 bm
Hunt 1994 PubMed
Kimbarowski 1967 translation_ZENODO
Kimbarowski 1967 PubMed
Kimbarowski 1967 German ch
Kimbarowski 1967 German bm
Mochalkin 1970 translation ZENODO
Mochalkin 1970 PubMed
Mochalkin 1970 Russian ch
Mochalkin 1970 Russian bm
Mochalkin 1974 translation ZENODO (same data as in 1970)
Mochalkin 1974 (OCR characters in Russian)
Mochalkin 1974 bm
Mochalkin 1974 PubMed
Mochalkin 1975 translation ZENODO (republication of 1970 with 2 vitC groups combined)
Mochalkin 1975 (OCR characters in Russian)
Mochalkin 1975 (OCR characters in Russian)
Mochalkin 1975 bm
Mochalkin 1975 PubMed
Pitt 1979 doi
Pitt 1979 PubMed
Pitt 1979 ch
Pitt 1979 bm
Tanaka 2000 Doi
Tanaka 2000 PubMed
Excluded trials
Cook 2007 doi
Cook 2007 PMC
Cook 2007 PubMed
Dahlberg 1944 doi
Dahlberg 1944 ch
Dahlberg 1944 bm
Hunt 1984 ch
Hunt 1984 bm
Hunt 1984 PubMed
Kahn 2011 doi
Kahn 2011 PubMed
Mahalanabis 2006a doi
Mahalanabis 2006b bm
Nathens 2002 PMC
Nathens 2002 PubMed
Nathens 2002 doi
Pico Sirvent 2013 Poster.pdf
Sirvent 2013 Poster.pdf
Scheunert 1949 ch
Scheunert 1949 bm
Sesso 2008 doi
Sesso 2008 PMC
Sesso 2008 PubMed
Wahed 2008 bm
******
Other references cited in the Cochrane Review
Akaike 2001 PubMed
Albaum 1996 doi
Albaum 1996 PubMed
Anderson 1973 PMC
Anderson 1972 PMC
Anderson 1972 and 1973 ch
Ashor 2014 doi
Ashton 1999 PubMed
Baik 2000 doi
Bakaev 2004 PubMed
Bakaev 2004 fulltext
Beisel 1982 AJCN
Bhoite 2011
Bissell 1980 PubMed
Bjordahl 2012 PubMed
Bloomfield 1999 doi
Bohnholzer 1937 translation ZENODO
Bohnholzer 1937 ch
Bohnholzer 1937 bm
see also:
Gunzel 1937 ch
Gunzel 1937 bm
Briggs 1984 Ref List
Bruno 2006 PubMed
Buffinton 1992 PubMed
Buffinton 1992 doi
Carpenter 1986 Cambridge
Carpenter 1986 Amazon
Carpenter 1986 BookReview
Carpenter 1986 BookReview
Cathcart 1981 doi
Cathcart 1981 PubMed
paper available via links
Cemek 2006 PubMed
Chakrabarti 1955 ch
Chakrabarti 1955 bm
Chakrabarti 1955 PubMed
Dalton 1962 ch
Dalton 1962
Dalton 1962 bm
Dalton 1962 PubMed
Dehghani 2014 PubMed
Dirlewanger 2002 PubMed
Dirlewanger 2002 doi
Doherty 1991 doi
Elwood 1976 doi
Elwood 1976 PMC
Elwood 1976 JECH
Elwood 1976 ch (54 KB)
Gaffey 1996 Doi
Galley 1996 PubMed
Gander 1936 translation
ZENODO
Gander 1936 ch
Gander 1936 bm
Goetzl 1974 PubMed
Goodwin 1998 doi
Goodwin 1998 PubMed
Hathcock 2005 AJCN
Hemilä 1984 doi
Hemilä 1992 doi
Hemilä 1992
Hemilä 1992 Manu
Hemilä 1992 PubMed
Hemilä 1996 doi
Hemilä 1996
Hemilä 1996 Manu
Hemilä 1996 PubMed
Hemilä 1996a doi
Hemilä 1996a
Hemilä 1996a Manu
Hemilä 1996a PubMed
Discussion:
Chalmers 1996
Hemilä 1996 Manu
Hemilä 1996
Hemilä 1996
Hemilä 1996b doi
Hemila 1996b
Hemilä 1996b Manu
Hemilä 1996b PubMed
Hemilä 1997 doi
Hemilä 1997 Manu
Hemilä 1997
Hemilä 1997a
Hemilä 1997b doi
Hemilä 1997b
Hemilä 1997b PubMed
Discussion
Discussion
Hemilä 1999 doi
Hemilä 1999_Manu
Hemilä 1999 PubMed
Hemilä 2004a doi
Hemilä 2004b doi
Hemilä 2006
Hemilä 2006
Hemilä 2007a doi
Hemilä 2007a PMC
Hemilä 2009a doi
Hemilä 2009a PMC
Hemilä 2011a doi
Hemilä 2011a PMC
Hemilä 2013a doi
https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8078152/
Hemilä 2013a web page
https://www.mv.helsinki.fi/home/hemila/CC/2013_Coch_Colds_CD000980.pdf
Hemilä 2013b doi
Hemilä 2013c doi
Hemilä 2013c PMC
Hemilä 2014 doi
Hemilä 2014 PMC
Hess 1920 (search book author = Hess)
Hess 1920 pages 88 and 99
Hess 1932 NEJM doi
Hess 1932 ch
Hess 1932 bm
also:
Hess 1932 JAMA doi
Higgins 2003 doi
Higgins 2003
Hochwald 1937 translation_
ZENODO
Hochwald 1937 ch
Hochwald 1937 bm
Holley 2011 PubMed
Hopstaken 2004 doi
Hopstaken 2004 PubMed
Hrobjartsson 2010 doi
Hughes 1988 ch
Hughes 1988 bm
Ioannidis 2007 doi
Ioannidis 2007 PubMed
IOM 2000 p. 95
Jones 1982 ch
Jones 1982 bm
Juraschek 2012 doi
Juraschek 2012 PubMed
Karlowski 1975 doi
Karlowski 1975 PubMed
Kiekara 1996 doi
Kiekara 1996 PubMed
Kinsman 1971 AJCN
Klenner 1948 ch
Klenner 1948
Klenner 1948
Klenner 1948
Klenner 1948 bm
paper available via links
Klenner 1951 ch
Klenner 1951
Klenner 1951
Klenner 1951
Klenner 1951 bm
paper available via links
Lau 2006 doi
Lau 2006 PubMed
Levine 1999 doi
Levine 1999 PubMed
Li 2006 J Nutr
Li 2006 PubMed
Louhiala 2014 doi
Louhiala 2014 hdl
Luberoff 1978 ch
Luberoff 1978 bm
Lydersen 2009 doi
Lydersen 2009 PubMed
Mandal 2011 doi
Mandal 2011 PubMed
Manning 2013 doi
Manning 2013 PMC
Manning 2013 PubMed
Manzella 1979 J Immunol
Manzella 1979 PubMed
May 2013 doi
May 2013 PMC
May 2013 PubMed
Melbye 1992 doi
Melbye 1992 PubMed
Merchant 2004 J Nutr
Mizgerd 2006 doi
Mosdol 2008 doi
Mosdol 2008 PubMed
Musher 2007 doi
Musher 2007 PubMed
Musher 2014 doi
Nualart 2003 doi
Nualart 2003 PubMed
Packer 1979 doi
Padayatty 2004 doi
Padayatty 2010 doi
Padayatty 2010 PubMed
Papoulidis 2011 PubMed
Paynter 2010 doi
Paynter 2010 PubMed
Pazzaglia 1983 doi
Pazzaglia 1983_PubMed
Pazzaglia 1983 ch
Pazzaglia 1983 bm
Powers 2008 doi
Powers 2008 PMC
Powers 2008 PubMed
Prina 2015 doi
Rayment 2003 doi
Rayment 2003 PubMed
Raynaud-Simon 2010 doi
Raynaud-Simon 2010 PubMed
Rice 2000 doi
Rice 2000 PubMed
Rivers 1987 doi
Rivers 1987 PubMed
Robertsson 1934 doi
Robertsson 1934 ch
Robertsson 1934 bm
Other old reviews on vitamin C and infections:
Perla 1937 pt I
Perla 1937 pt II
Clausen_1934_doi
Clausen 1934
Ruuskanen 2011 doi
Ruuskanen 2011 PubMed
Sabin 1939 doi
Sabin 1939 PMC
Sadeghpour 2015 PubMed
Sadeghpour 2015 PMC
Sarzaeem 2014 Translation_ZENODO
Schleicher 2009 doi
Schleicher 2009 PubMed
Self_2015
Siegel 1975 doi
Slotkin 1944_doi
Slotkin 1944
Slotkin 1944
Slotkin 1944
Sterne 2011 doi
Sterne 2011 PubMed
Swingler 1998 doi
Syrjälä 1998 doi
Terrin 2005 doi
Thomas 1978 PMC
Walker 2013 doi
Walker 2013 PubMed
Wang 1997 doi
Wang 1997 PubMed
Wang 2012 PubMed
Wang 2013 doi
Wang 2013 PubMed
Webb 2007 doi
WHO 1999b doi
WHO 1999b fulltext
Young 1994 doi
Young 1994 PubMed
Zhang 2011 doi
Zhang_2011 PubMed
