β-Carotene
effect on mortality depeds on smoking and on vitamins C and E Hemilä H The
effect of β-carotene on the mortality of male smokers is modified by
smoking and by vitamins C and E: evidence against a uniform effect of
nutrient
J Nutr Sci 2020 https://doi.org/10.1017/jns.2020.3 https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7082716
β-Carotene increases the risk of pneumonia, depending on smoking
Hemilä H Effect of β-Carotene
Supplementation on the Risk of Pneumonia Is Heterogeneous in Males:
Effect Modification by Cigarette Smoking
J Nutr Sci Vitaminol (Tokyo) 2018 https://doi.org/10.3177/jnsv.64.374
The
effect of β-carotene on common cold incidence is heteroteneous
depending on age and smoking No
good evidence of preventive effects in any group, but evidence of harm
in some groups
Hemilä H The effect of β-carotene
on common
cold incidence is modified by age and smoking: evidence against a
uniform effect in a nutrient-disease relationship.
Nutrition and Dietary Supplements 2010 https://doi.org/10.2147/NDS.S13299 https://www.dovepress.com/article_5490.t2368605
The
harms of β-carotene supplementation may be caused by carotene cleavage
products including vitamin A derivatives
Hemilä H, Wikström M. Retinoids activate
superoxide production by polymorphonuclear leucocytes.
Scand J Immunol. 1985 https://www.ncbi.nlm.nih.gov/pubmed/2986277
Letters
and commentaries in English
Hemilä H Antioxidants are not
identical and their effects are not uniform over the population
[Feedback].
[Comments on the Cochrane review “Antioxidant
supplements for prevention of mortality in healthy participants and
patients with various diseases” by Bjelakovic G et al.] https://helda.helsinki.fi/handle/10138/136201
Vitamin
D
Problems
in a meta-analysis in BMJ on vitamin D and the common cold
Hemilä H Statistical problems in
the vitamin D and respiratory infection meta-analysis
BMJ eLetter 2017 https://www.bmj.com/content/356/bmj.i6583/rr-3